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The Novelty of mRNA Viral Vaccines and Potential Harms: A Scoping Review
mRNA Off to a Bad Start but Future May be Brighter
By Peter A. McCullough, MD, MPH
We all have the tendency to paint issues with a broad brush. That is to see things one way for intellectual simplicity. “All pharmaceuticals are bad” or “I don’t trust any vaccine.” It is even more tempting to take a negative view on all new technology when the product launch in humans fails to a large degree.
These old mental saws could apply to mRNA vaccines. Halma et al have published a scoping review of lipid nanoparticle-mRNA products with fair balance causing the reader to consider future possibilities. The COVID-19 vaccines are known to be unsafe for several reasons: 1) the Wuhan Spike protein damages cells, tissues, organs, and causes blood clotting, 2) the lipid nanoparticles may have toxicity from the PEG or polysorbate 80 or from syncytia formation, 3) the mRNA appears to be resistant to ribonucleases and is not broken down in the body. As some point the mRNA or fragments could interfere with gene function or alter other microRNAs that are managing the human genome.
The Halma paper points out that safe mRNA products are possible. For example, properly designed mRNA coding for normal proteins that are deficient or ones that are sufficiently humanized and not recognized by the body as foreign could indeed become part of the future pharmacopeia. But there is no doubt that the first use of mRNA on a mass, indiscriminate scale has been a disaster with the COVID-19 vaccine campaign.
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