Twenty Eight Mechanisms of Kidney Injury with COVID-19 Vaccination
Exhaustive Review Finds Common Theme of Inflammation from Cytokines and Auto-Immunity
By Peter A. McCullough, MD, MPH
I had a patient this year who presented far along the path of chronic kidney disease requiring initiation of renal replacement therapy otherwise known as dialysis. I wondered if COVID-19 vaccination could injure the kidneys as it does the heart, brain, and so many other organs.
The kidneys receive about 25% of cardiac output and are continuously filtering the blood. Among the vaccinated, Brogna et al have shown about half of the vaccinated have detectable, full length trimerized vaccine Spike protein in the bloodstream. It makes sense that both mRNA and Spike protein could settle in the kidney, cause expression of Spike protein and possibly other frameshifted peptide fragments on the cell surface of glomerular cells (renal epithelial, podocytes, mesangial) and because of the constant blood flow and urine exposure, product a hotspot for immune attack against the organ.
A review by Vudathaneni et al, described 28 published mechanisms of kidney injury and renal damage from COVID-19 vaccination. Most of the pathways involve inflammation from either direct cytokine damage or auto-immunity.
The take home message for doctors, nurses, and vaccinated patients is that renal function should be assessed with serum creatinine, cystatin-C, blood urea nitrogen, and urine albumin:creatinine ratio. If there is evidence of damage, then auto-immune markers including ANA, ANCA, RF, and anti–cyclic citrullinated peptide (anti-CCP) antibody should be drawn. Given the broad array of pathology, nephrologists should have a low threshold for renal biopsy so an accurate diagnosis can be made.
My fear is the with so many pressing medical problems including myocarditis, cardiac arrest, stroke, and blood clots, that renal damage may be overlooked and when the medical community and patients discover it, it may be too late to intervene.
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Peter A. McCullough, MD, MPH
President, McCullough Foundation
I agree that the mRNA COVID vaccines injure the kidneys. Here is the evidence that I found:
https://colleenhuber.substack.com/p/nz-fudged-the-data-on-how-the-kidneys
PRAYER AND FASTING
Will you join me with prayer and fasting for the redemption of our country and for justice and reparations for the J6 political prisoners on the 6th day of every month until Election Day and until the J6’ers are freed from their political persecution? You may eat all the bread and drink all the water you want on those days. I usually have 2 slices of bread with a large glass of water three times a day on those days. I will meditate on the Word and ask God, as Abraham had done,according to Genesis 18:23-33 “‘Wilt though indeed destroy the righteous with the wicked? Suppose there are 50 righteous within the city; wilt thou then destroy the city; wilt thou then destroy the place and not spare it for the 50 righteous who are in it? Far be it from thee to do such a thing, to slay the righteous with the wicked, so that the righteous fare as the wicked! Far be that from thee! Shall not the Judge of all the earth do right?’ And the Lord said, ‘If I find at Sodom 50 righteous in the city, I will spare the whole place for their sake.’” And Abraham continued to bargain with the Lord asking if there were only 10 righteous men in the city, would he spare the city. Well we know what happened to Sodom and Gomorrah. I think we have more than 50 righteous people in our country and I hope and pray that God will consider it worth saving. I hope and pray that we can return to traditional American values and the honoring and reverence for our Constitution which, I believe, was divinely inspired. If you will join me in prayer and fasting, please send me a comment.