Veterinary Replicon Vaccines
Massive Genetic Effort in Veterinary Medicine Described as "Elegant"
By Peter A. McCullough, MD, MPH
The news has been full for months with stories about striking Dutch farmers, Chinese acquisition of foreign farms, projected food shortages, and now vaccination of plants and animals in the food supply. Compared with human medicine, veterinary medicine is far ahead in genetic vaccine technologies. One of the reasons is that the life cycle of a livestock is sufficiently short that clinical studies simply aim to demonstrate efficacy with reasonable safety as a secondary goal.
Hikke and Pijlman describe “replicon” vaccines in development and approved products. “To increase the potency by stimulating multiple immune pathways simultaneously, nucleic acid vaccines based on self-replicating viral RNAs (replicon vaccines) have been developed. An important feature that sets replicon vaccines apart from LAV or viral-vectored vaccines is their inability to spread from cell to cell. Replicons do not code for viral structural proteins required for encapsidation but instead code for a heterologous gene of interest. Thus, replicons are not infectious and are limited to a single round of replication. In its most simple form, a replicon is a cloned viral complementary DNA (cDNA) with the structural genes removed.”
One could imagine the danger if such a “replicon” was devised for humans, but coded for a foreign and damaging protein such as the WIV SARS-CoV-2 Spike or Influenza hemagglutinin (HA). The inability to not only shut off antigen production but to control continued amplification beyond one round of RNA could overwhelm the body with damaging antigen production. Expression of foreign proteins/antigens on the cell surface over time is bound to generate autoimmunity and a variety of problems.
In summary, safety for veterinary use is not the same as for human use. We will need to take a careful look at advances in human medicine that attempt to parallel those taken with farm animals, livestock, and other elements of the food supply.
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I won't be getting any shots for my pets anymore either. Last time they had rabies one almost died.
Something is hellishly wrong with our word...science is not science...and who is pushing this? And why? and what is the incentive? I just don't get it at all anymore, despite the tons of money being thrown at everyone along the lines of authority and the deliverers..(docs and vets).....when we do not know the ultimate result.
It’s time to seriously think about getting your dairy and meat from Amish farmers.